Uma pesquisa divulgada pela Universidade Harvard, nos Estados Unidos, insinua que a leucina, um aminoácido amplamente encontrado na dieta, pode atrapalhar o tratamento do tipo mais comum de câncer de mama. Essa substância atua na saúde dos músculos e na manutenção das demais células do corpo – e está em carnes, leites e proteínas vegetais, como as leguminosas.
Os cientistas fizeram testes em células isoladas no laboratório, e descobriram que aumentar os níveis de leucina em conjunto com um tipo de tratamento também intensificava o crescimento do câncer de mama. Por outro lado, restringir o nutriente suprimia a atividade maligna.
Esse comportamento foi observado no tumor de mama com receptor de estrogênio. Esse subtipo responde por quase 70% dos casos da enfermidade.
A expectativa é que o achado seja usado para criar remédios que bloqueiem a ação da leucina nos tumores e, quem sabe, para desenhar intervenções na alimentação. O grupo testa agora essa segunda possibilidade, averiguando se cortar o composto da dieta de roedores com câncer de mama trará algum benefício.
Ponderações necessárias
A relação entre leucina e resistência ao tratamento do câncer de mama com receptor de estrogênio não está bem estabelecida. Os estudos são preliminares, com experimentos realizados em cultura de células e camundongos.
Ou seja, não dá para extrapolar o achado para seres humanos. Fora que, quando pensamos na restrição de leucina, estamos falando em tirar proteínas da dieta, o que pode levar a perda de massa muscular, de força, e, assim, até a um prejuízo da resposta ao tratamento.
Ou seja, nem pense em fazer isso, principalmente por conta própria.
Saúde Abril
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